柯逢春 (Ke, Ferng-Chun)
職 稱 副教授
出生年 1956
最高學歷 美國伊利諾大學博士
專 長 細胞生理、細胞生化
E-mail fck@ccms.ntu.edu.tw
研究室 生命科學館 744 室
電話 02-23630231 ext.3829
近年研究主題:
細胞老化(Cellular Senescence)
1. 粒腺體在崔發細胞老化上的分子機制。
2. 抑癌因子迴路P53-MDM2-Rb-P300/CBP、PTEN-AKT-TSCs-TORC在細胞老化的角色。
研究室簡介:發生細胞學研究室
  本研究室的設備包含:(1) 從事分子生物實驗的配備;(2) 從事蛋白質生化及免疫化學的系統;(3) 細胞培養室。
代表著作:

近五年著作
Y-T Huang, J-J Hwang, P-P Lee,F-C Ke, J-H Huang, C-J Huang, C Kandaswami, E Middleton Jr & M-T Lee (1999) Effects of luteolin and quercetin, inhibitors of tyrosine kinase on cell growth and metastasis-associated properties in A431. Br. J. Pharmacol. 128, 999-1010
C-H Teng, F-C Ke, M-T Lee, L Chen & J-J Hwang (2000) Pituitary adenylate cyclase-activating polypeptide acts synergistically with relaxin in modulating ovarian cell function in rats. J. Endocrinol. 167, 61-69
S-W Lin, M-T Lee, F-C Ke, P-P H. Lee, C-J Huang, M. M. Ip, L. Chen &J-J Hwang (2001) TGFb1 stimulates the secretion of matrix metalloproteinase 2 (MMP2) and the invasive behavior in human ovarian cancer cells, which is surpressed by MMP inhibitor BB3103. Clinical,& Experimental Metastasis 18, 493-499
Y-T Huang, J-J Hwang, L-T Lee, C. Liebow, P-P H Lee, F-C Ke, T-B Lo, A. V. Schally & M-T Lee (2002) Inhibitory effects of a luteinizing-releasing hormone agonist on basal and epidermal growth factor-induced cell proliferation and metastasis-associated properties in human epidermoid carcinoma A431 cells. Int. J. Cancer 99, 505-513
L-T Lee, Huang Y-T, Hwang J-J, P-P H. Lee, F-C Ke, M. P. Nair, C. Kanadaswami & M-T Lee (2002) Blockade of the epidermal growth factor receptor tyrosine kinase activity by quercetin and luteolin leads to growth inhibition and apoptosis of pancreatic tumor cells. Anticancer Res. 22, 1615-1628
Ke, F-C, Chuang, L-C, Lee, M-T, Chen, Y J, Lin, S-W, Wang, P S., Stocco, D M., Hwang, J-J (2004) Modulatory Role of Transforming Growth Factor β1 and Androstenedione on Follicle-Stimulating Hormone-Induced Gelatinase Secretion and Steroidogenesis in Rat Granulosa Cells. Biology of Reproduction 70, 1292-1298

開設課程:
205 322A0 動物生理學實驗甲
205 36300 細胞生物學
B43 U1160 分子細胞生物學
B43 U1090 細胞週期
B43 M0330 細胞老化專題討論

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